Searchable abstracts of presentations at key conferences in endocrinology

ea0070aep922 | Thyroid | ECE2020

Impact ofhypothyroidism on early preneoplastic changes at the transcriptomic level in mammalian cells

Hanusek Karolina , Duda Monika , Piekiełko-Witkowska Agnieszka

Introduction: Studies suggest that disturbed thyroid hormones (TH) homeostasis may lead to increased cancer risk. However, the exact role of TH in cancerogenesis is unknown. We have previously identified 15 genes linked with TH signaling in 7 cancer types and 10.967 cancer patients. Here, we investigated the influence of hypothyroidism on the expression of these 15 genes in rat tissues/organs from which the previously identified, TH-related cancer types originate.<p class=...